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Norfluoxetine hydrochloride is an active N-demethylated metabolite of Fluoxetine, functioning as a selective serotonin (5-HT) reuptake inhibitor. It is metabolized by cytochrome P450 (CYP) 2D6, CYP2C19, and CYP3A4. This compound also exhibits anticonvulsant activity and inhibits CaV3.3 T current (IC50 = 5 μM).
Active N-demethylated metabolite of fluoxetine.
Selective serotonin (5-HT) reuptake inhibitor.
Metabolized by cytochrome P450 (CYP) 2D6, CYP2C19, and CYP3A4.
Inhibits 5-HT uptake.
Inhibits CaV3.3 T current (IC50 = 5 μM).
Exhibits anticonvulsant activity.
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Oxybuprocaine hydrochloride (Benoxinate hydrochloride) reversibly blocks sodium channels and prevents propagation of painful nerve impulses in the cornea, conjunctiva, and sclera. It is used especially in ophthalmology and otolaryngology.
Blocks sodium channels.
Prevents nerve impulse propagation in the cornea, conjunctiva, and sclera.
Used in ophthalmology and otolaryngology.
10 mM, 1 mL solution in DMSO.
Purity of 99.93%.
Store at -80°C for 6 months or -20°C for 1 month in solvent, sealed, away from moisture.
Ship at room temperature if less than 2 weeks.
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